Influence of Depressive Symptoms on Dopaminergic Treatment of Parkinson’s Disease
Identifieur interne : 000A32 ( Main/Exploration ); précédent : 000A31; suivant : 000A33Influence of Depressive Symptoms on Dopaminergic Treatment of Parkinson’s Disease
Auteurs : Alexandru Hanganu [Canada] ; Clotilde Degroot [Canada] ; Oury Monchi [Canada] ; Christophe Bedetti [Canada] ; Béatriz Mejia-Constain [Canada] ; Anne-Louise Lafontaine [Canada] ; Sylvain Chouinard [Canada] ; Marie-Andrée Bruneau [Canada]Source :
- Frontiers in Neurology [ 1664-2295 ] ; 2014.
Abstract
Url:
DOI: 10.3389/fneur.2014.00188
PubMed: 25309508
PubMed Central: 4174860
Affiliations:
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Influence of Depressive Symptoms on Dopaminergic Treatment of Parkinson’s Disease</title><author><name sortKey="Hanganu, Alexandru" sort="Hanganu, Alexandru" uniqKey="Hanganu A" first="Alexandru" last="Hanganu">Alexandru Hanganu</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Centre de Recherche, Institut Universitaire de Gériatrie de Montréal</institution>,<addr-line>Montreal, QC</addr-line>,<country>Canada</country></nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Degroot, Clotilde" sort="Degroot, Clotilde" uniqKey="Degroot C" first="Clotilde" last="Degroot">Clotilde Degroot</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Centre de Recherche, Institut Universitaire de Gériatrie de Montréal</institution>,<addr-line>Montreal, QC</addr-line>,<country>Canada</country></nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Monchi, Oury" sort="Monchi, Oury" uniqKey="Monchi O" first="Oury" last="Monchi">Oury Monchi</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Centre de Recherche, Institut Universitaire de Gériatrie de Montréal</institution>,<addr-line>Montreal, QC</addr-line>,<country>Canada</country></nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Department of Radiology, Faculty of Medicine, University of Montreal</institution>,<addr-line>Montreal, QC</addr-line>,<country>Canada</country></nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Bedetti, Christophe" sort="Bedetti, Christophe" uniqKey="Bedetti C" first="Christophe" last="Bedetti">Christophe Bedetti</name><affiliation wicri:level="1"><nlm:aff id="aff3"><institution>Centre d’Études Avancées en Médecine du Sommeil, Hôpital du Sacré Coeur de Montréal</institution>,<addr-line>Montreal, QC</addr-line>,<country>Canada</country></nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Mejia Constain, Beatriz" sort="Mejia Constain, Beatriz" uniqKey="Mejia Constain B" first="Béatriz" last="Mejia-Constain">Béatriz Mejia-Constain</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Centre de Recherche, Institut Universitaire de Gériatrie de Montréal</institution>,<addr-line>Montreal, QC</addr-line>,<country>Canada</country></nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Lafontaine, Anne Louise" sort="Lafontaine, Anne Louise" uniqKey="Lafontaine A" first="Anne-Louise" last="Lafontaine">Anne-Louise Lafontaine</name><affiliation wicri:level="1"><nlm:aff id="aff4"><institution>Movement Disorders Unit, McGill University Health Center</institution>,<addr-line>Montreal, QC</addr-line>,<country>Canada</country></nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff5"><institution>Department of Neurology, Montreal Neurological Hospital</institution>,<addr-line>Montreal, QC</addr-line>,<country>Canada</country></nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Chouinard, Sylvain" sort="Chouinard, Sylvain" uniqKey="Chouinard S" first="Sylvain" last="Chouinard">Sylvain Chouinard</name><affiliation wicri:level="1"><nlm:aff id="aff6"><institution>Unité des troubles du mouvement André Barbeau, Centre Hospitalier de l’Université de Montréal</institution>,<addr-line>Montreal, QC</addr-line>,<country>Canada</country></nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Bruneau, Marie Andree" sort="Bruneau, Marie Andree" uniqKey="Bruneau M" first="Marie-Andrée" last="Bruneau">Marie-Andrée Bruneau</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Centre de Recherche, Institut Universitaire de Gériatrie de Montréal</institution>,<addr-line>Montreal, QC</addr-line>,<country>Canada</country></nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">25309508</idno><idno 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xml:lang="en" level="a" type="main">Influence of Depressive Symptoms on Dopaminergic Treatment of Parkinson’s Disease</title><author><name sortKey="Hanganu, Alexandru" sort="Hanganu, Alexandru" uniqKey="Hanganu A" first="Alexandru" last="Hanganu">Alexandru Hanganu</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Centre de Recherche, Institut Universitaire de Gériatrie de Montréal</institution>,<addr-line>Montreal, QC</addr-line>,<country>Canada</country></nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Degroot, Clotilde" sort="Degroot, Clotilde" uniqKey="Degroot C" first="Clotilde" last="Degroot">Clotilde Degroot</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Centre de Recherche, Institut Universitaire de Gériatrie de Montréal</institution>,<addr-line>Montreal, QC</addr-line>,<country>Canada</country></nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Monchi, Oury" sort="Monchi, Oury" uniqKey="Monchi O" first="Oury" last="Monchi">Oury Monchi</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Centre de Recherche, Institut Universitaire de Gériatrie de Montréal</institution>,<addr-line>Montreal, QC</addr-line>,<country>Canada</country></nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Department of Radiology, Faculty of Medicine, University of Montreal</institution>,<addr-line>Montreal, QC</addr-line>,<country>Canada</country></nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Bedetti, Christophe" sort="Bedetti, Christophe" uniqKey="Bedetti C" first="Christophe" last="Bedetti">Christophe Bedetti</name><affiliation wicri:level="1"><nlm:aff id="aff3"><institution>Centre d’Études Avancées en Médecine du Sommeil, Hôpital du Sacré Coeur de Montréal</institution>,<addr-line>Montreal, QC</addr-line>,<country>Canada</country></nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Mejia Constain, Beatriz" sort="Mejia Constain, Beatriz" uniqKey="Mejia Constain B" first="Béatriz" last="Mejia-Constain">Béatriz Mejia-Constain</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Centre de Recherche, Institut Universitaire de Gériatrie de Montréal</institution>,<addr-line>Montreal, QC</addr-line>,<country>Canada</country></nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Lafontaine, Anne Louise" sort="Lafontaine, Anne Louise" uniqKey="Lafontaine A" first="Anne-Louise" last="Lafontaine">Anne-Louise Lafontaine</name><affiliation wicri:level="1"><nlm:aff id="aff4"><institution>Movement Disorders Unit, McGill University Health Center</institution>,<addr-line>Montreal, QC</addr-line>,<country>Canada</country></nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff5"><institution>Department of Neurology, Montreal Neurological Hospital</institution>,<addr-line>Montreal, QC</addr-line>,<country>Canada</country></nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Chouinard, Sylvain" sort="Chouinard, Sylvain" uniqKey="Chouinard S" first="Sylvain" last="Chouinard">Sylvain Chouinard</name><affiliation wicri:level="1"><nlm:aff id="aff6"><institution>Unité des troubles du mouvement André Barbeau, Centre Hospitalier de l’Université de Montréal</institution>,<addr-line>Montreal, QC</addr-line>,<country>Canada</country></nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Bruneau, Marie Andree" sort="Bruneau, Marie Andree" uniqKey="Bruneau M" first="Marie-Andrée" last="Bruneau">Marie-Andrée Bruneau</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Centre de Recherche, Institut Universitaire de Gériatrie de Montréal</institution>,<addr-line>Montreal, QC</addr-line>,<country>Canada</country></nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author></analytic><series><title level="j">Frontiers in Neurology</title><idno type="eISSN">1664-2295</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><bold>Introduction:</bold> Depressive symptoms are very common in patients with Parkinson’s disease (PD) and have a significant impact on the quality of life. Dopaminergic medication has been shown to have an influence on the development of depressive symptoms.</p><p><bold>Materials and methods:</bold> The present study analyzed two groups of non-demented patients with PD, with and without depressive symptoms, and reported the correlations between antiparkinsonian medication [specifically levodopa (<sc>l</sc>-DOPA) and dopaminergic agonists] with depressive symptoms.</p><p><bold>Results:</bold> A strong statistically significant positive correlation between <sc>l</sc>-DOPA dosages and the level of depressive symptoms has been revealed, suggesting that higher <sc>l</sc>-DOPA dosages correlate with a worsening of depressive status. No significant correlation was found with dopamine agonists.</p><p><bold>Discussion:</bold> The results of this study show that in patients with PD, higher <sc>l</sc>-DOPA dosages correlate with worse depressive symptoms. From this point of view, PD patients need to be better diagnosed with respect to depressive symptoms and need additional treatment adjustment when clinical manifestations of depression are present. Clinicians must be aware that dopaminergic drugs are not sufficient to alleviate depressive symptoms.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Rijk, Mc" uniqKey="Rijk M">MC Rijk</name></author><author><name sortKey="Tzourio, C" uniqKey="Tzourio C">C Tzourio</name></author><author><name sortKey="Breteler, Mm" uniqKey="Breteler M">MM Breteler</name></author><author><name sortKey="Dartigues, Jf" uniqKey="Dartigues J">JF Dartigues</name></author><author><name sortKey="Amaducci, L" uniqKey="Amaducci L">L Amaducci</name></author><author><name sortKey="Lopez Pousa, S" uniqKey="Lopez Pousa S">S Lopez-Pousa</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Von Campenhausen, S" uniqKey="Von Campenhausen S">S von Campenhausen</name></author><author><name sortKey="Bornschein, B" uniqKey="Bornschein B">B Bornschein</name></author><author><name sortKey="Wick, R" uniqKey="Wick R">R 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uniqKey="Garolera M">MT Garolera</name></author><author><name sortKey="Cubo, E" uniqKey="Cubo E">E Cubo</name></author><author><name sortKey="Navas, I" uniqKey="Navas I">I Navas</name></author><author><name sortKey="Quintana, S" uniqKey="Quintana S">S Quintana</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kuhn, W" uniqKey="Kuhn W">W Kuhn</name></author><author><name sortKey="Heye, N" uniqKey="Heye N">N Heye</name></author><author><name sortKey="Muller, T" uniqKey="Muller T">T Müller</name></author><author><name sortKey="Kraus, P" uniqKey="Kraus P">P Kraus</name></author><author><name sortKey="Klotz, P" uniqKey="Klotz P">P Klotz</name></author><author><name sortKey="Friedrich, B" uniqKey="Friedrich B">B Friedrich</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Canada</li></country></list><tree><country name="Canada"><noRegion><name sortKey="Hanganu, Alexandru" sort="Hanganu, Alexandru" uniqKey="Hanganu A" first="Alexandru" last="Hanganu">Alexandru Hanganu</name></noRegion><name sortKey="Bedetti, Christophe" sort="Bedetti, Christophe" uniqKey="Bedetti C" first="Christophe" last="Bedetti">Christophe Bedetti</name><name sortKey="Bruneau, Marie Andree" sort="Bruneau, Marie Andree" uniqKey="Bruneau M" first="Marie-Andrée" last="Bruneau">Marie-Andrée Bruneau</name><name sortKey="Chouinard, Sylvain" sort="Chouinard, Sylvain" uniqKey="Chouinard S" first="Sylvain" last="Chouinard">Sylvain Chouinard</name><name sortKey="Degroot, Clotilde" sort="Degroot, Clotilde" uniqKey="Degroot C" first="Clotilde" last="Degroot">Clotilde Degroot</name><name sortKey="Lafontaine, Anne Louise" sort="Lafontaine, Anne Louise" uniqKey="Lafontaine A" first="Anne-Louise" last="Lafontaine">Anne-Louise Lafontaine</name><name sortKey="Lafontaine, Anne Louise" sort="Lafontaine, Anne Louise" uniqKey="Lafontaine A" first="Anne-Louise" last="Lafontaine">Anne-Louise Lafontaine</name><name sortKey="Mejia Constain, Beatriz" sort="Mejia Constain, Beatriz" uniqKey="Mejia Constain B" first="Béatriz" last="Mejia-Constain">Béatriz Mejia-Constain</name><name sortKey="Monchi, Oury" sort="Monchi, Oury" uniqKey="Monchi O" first="Oury" last="Monchi">Oury Monchi</name><name sortKey="Monchi, Oury" sort="Monchi, Oury" uniqKey="Monchi O" first="Oury" last="Monchi">Oury Monchi</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Canada/explor/ParkinsonCanadaV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000A32 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000A32 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Canada
|area= ParkinsonCanadaV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= PMC:4174860
|texte= Influence of Depressive Symptoms on Dopaminergic Treatment of Parkinson’s Disease
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:25309508" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a ParkinsonCanadaV1
| This area was generated with Dilib version V0.6.29. |  |